How Russia has developed an mRNA vaccine against cancer

Russia has developed an mRNA vaccine against cancer, Russian news agency TASS has reported. The vaccine will be distributed to cancer patients for free, General Director of the Radiology Medical Research Center of the Russian Ministry of Health, Andrey Kaprin, told Radio Rossiya.

The vaccine has been developed in collaboration with several research centers and is expected to be released for public use by early 2025.

The vaccine’s pre-clinical trials had shown that it suppresses tumor development and potential metastases, Director of the Gamaleya National Research Center for Epidemiology and Microbiology Alexander Gintsburg told TASS.

What Is An mRNA Vaccine?

mRNA or messenger-RNA vaccines use specific parts of the infectious agent like its protein, sugar, or coating. mRNA vaccine gives a message to our cells to make a protein or even just a piece of a protein which are like those of the virus. The protein then triggers an immune response inside our bodies.
Can AI Help Generate Personalised Cancer Vaccines?

Earlier, in an interview with TASS, Mr Gintsburg had said that the use of artificial neural networks could bring down the duration of computing required to create a personalized cancer vaccine to less an hour.

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“Now it takes quite long to build [personalized vaccines] because computing of how a vaccine, or customized mRNA, should look like uses matrix methods, in mathematical terms. We have involved the Ivannikov Institute which will rely on AI in doing this math, namely neural network computing where these procedures should take about half an hour to an hour,” Russia’s vaccine chief said.
Andrey Kaprin, General Director of the Radiology Medical Research Center of the Russian Ministry of Health, told Radio Rossiya, “Russia has developed its own mRNA vaccine against cancer, it will be distributed to patients free of charge.”

Pre-clinical trials suggest the vaccine inhibits tumor growth and the spread of cancer, according to Alexander Gintsburg, Director of the Gamaleya National Research Center for Epidemiology and Microbiology. He stated that, “The vaccine’s pre-clinical trials had shown that it suppresses tumor development and potential metastases.”
Earlier this year, Russian President Vladimir Putin hinted at progress in cancer vaccine development. Gintsburg also discussed the potential of artificial intelligence to speed up the creation of personalized cancer vaccines, potentially reducing the process to under an hour. He explained, “Now it takes quite long to build [personalized vaccines] because computing how a vaccine, or customized mRNA, should look like uses matrix methods, in mathematical terms. We have involved the Ivannikov Instit ..

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In contrast, mRNA vaccines function by delivering genetic instructions that enable the body’s cells to produce a specific cancer protein, known as an antigen. This process trains the immune system to recognize and create antibodies against the protein.

When the same antigens are detected on tumor cells, the immune system launches an attack against them, targeting the cancer.

Unlike COVID-19 mRNA vaccines, which are designed to target a single antigen—the spike protein of the corona ..

Read more at:
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